Up until about 3 years ago, the answer was "no." I don't know why I was such a late adopter; I wasn't opposed to using them. I just didn't have the money for a good one, and wasn't noticing a huge gap between what I was doing and what I could do if I invested in a Bible Study software.
3 years ago I repented, and purchased Logos.
This isn't a commercial for Logos, but I did my research when I got ready to make the investment, and for a pastor or general Bible student, Logos is far and away the best investment.
At my fingertips, I have hundreds of searchable books. Want to know what John Calvin, or John Piper, or John MacArthur said about Ephesians 1:3? Just type "Ephesians 1:3" in your search box, direct it to your electronic books, and in .41 seconds I can have each of those books open to each place they mention the verse.
Wondering about the meaning of the Greek word for "sick" in James 5:14? You're one click away. Don't know Greek? It doesn't matter - the resource will explain the meaning for you.
Seriously, if I had invested in Logos 10 years ago, I could have graduated from seminary a year earlier. No exaggeration.
The only problem with Logos is that it is not necessarily very intuitive. That is, you can't pull it out of the box and figure out all its functions on your own. Enter Morris Proctor. This guy is a Logos Jedi, and a tremendous communicator. He conducts various levels of training seminars for Logos users and completely opens up the software for you whether you're a seminary professor or a small group leader with no formal Bible training. The first seminar I went to turned out to jump-start a complete paradigm shift in my Bible study.
The basic version of Logos and a MP Seminar will set you back a couple hundred dollars, but if your experience is anything like mine, it will be some of the best money you invest this year.